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Quizzes > Quizzes for Business > Healthcare

Test Your Knowledge: Donor Tissue Recovery Time Limits Quiz

Challenge Yourself on Tissue Retrieval Deadlines

Difficulty: Moderate
Questions: 20
Learning OutcomesStudy Material
Colorful paper art depicting a quiz on donor tissue recovery time limits.

Ready to test your mastery of donor tissue guidelines and recovery time limits? This quiz challenges healthcare professionals, transplant coordinators, and students with 15 multiple-choice questions that simulate real-world organ recovery scenarios. By taking this free practice quiz, participants will deepen their understanding of allowable retrieval windows and compliance standards. You can freely modify any question in our editor to suit your study needs. For more related practice, explore the Recovery Fundamentals Knowledge Quiz or Service Recovery Knowledge Quiz, or browse all quizzes.

What is the maximum recommended warm ischemia time for heart tissue recovery?
30 minutes
4 hours
1 hour
6 hours
The heart is highly sensitive to warm ischemia and should be recovered within 30 minutes to preserve myocardial viability. Extended warm ischemia leads to irreversible cellular damage.
What is the typical maximum cold ischemia time for a kidney graft?
24 hours
12 hours
6 hours
36 hours
Kidneys tolerate cold ischemia better than many organs, with guidelines allowing up to 36 hours of cold storage before transplantation. Prolonged cold ischemia beyond this increases risk of delayed graft function.
What is the maximum cold ischemia time for liver transplant viability?
12 hours
4 hours
8 hours
24 hours
Livers are recommended to stay within 12 hours of cold ischemia to maintain adequate graft function. Beyond this period, the risk of ischemia-reperfusion injury increases markedly.
Corneal tissue should be recovered within how many hours post-mortem to ensure cell viability?
6 hours
12 hours
24 hours
48 hours
Corneas are ideally recovered within 12 hours of death to ensure endothelial cell viability. Recovery beyond this window risks significant cell loss and reduced graft success.
Which organ has the shortest allowable recovery window due to high susceptibility to warm ischemia?
Liver
Cornea
Kidney
Heart
The heart must be recovered very rapidly (within 30 minutes of warm ischemia) due to its extreme sensitivity to oxygen deprivation. Other tissues have longer tolerated windows.
What is the recommended maximum cold ischemia time for lung transplantation?
6 hours
4 hours
8 hours
12 hours
Lungs are typically washed with preservation solution immediately and stored cold, with a recommended limit of 6 hours of cold ischemia. Exceeding this increases primary graft dysfunction risk.
Under standard guidelines, what is the maximum cold ischemic time for pancreas grafts?
24 hours
10 hours
12 hours
6 hours
Pancreas transplants are sensitive to ischemia and should be transplanted within 12 hours of cold storage. Longer durations risk acinar cell degradation and pancreatitis post-transplant.
What is the typical maximum cold ischemia time for small bowel recovery?
12 hours
6 hours
15 hours
9 hours
Small bowel tissue is delicate and tolerates up to 6 hours of cold ischemia. Beyond this, mucosal barrier integrity and graft function decline rapidly.
Which of the following factors does NOT typically influence allowable ischemia times for donor tissues?
Time of day
Preservation solution
Organ type
Donor age
Ischemia times are driven by organ-specific tolerance, donor condition, and preservation methods, not by the time of day when recovery occurs. Circadian effects are not a regulatory consideration.
Musculoskeletal tissue for grafting must generally be recovered within how many hours post-mortem?
12 hours
72 hours
36 hours
24 hours
Musculoskeletal tissues are typically recovered within 24 hours of death to reduce bacterial contamination and maintain cell viability. Extended intervals increase infection risk.
Cardiac valve tissues are usually recovered within what maximum post-mortem interval?
48 hours
72 hours
96 hours
24 hours
Heart valves can be safely recovered up to 48 hours after death, provided strict temperature control is maintained to prevent tissue degradation and contamination.
Which of the following is most critical for maintaining tissue viability during storage?
Temperature control
Donor demographics
Labeling method
Recovery team size
Consistent temperature control is essential to slow metabolism and prevent cellular injury. Improper temperature is the leading cause of loss of tissue viability during storage.
How does an elevated donor body temperature at time of death affect allowable ischemia times?
It has no effect
It shortens the allowable time
It only affects corneal tissue
It lengthens the allowable time
Higher body temperatures accelerate cellular metabolism and degradation, thereby reducing the time tissues can remain viable without preservation interventions.
For best outcomes, organs should be perfused with preservation solution within how many minutes of procurement?
240 minutes
60 minutes
30 minutes
120 minutes
Rapid perfusion (within 30 minutes) with cold preservation solution minimizes warm ischemia and helps maintain cellular integrity. Delays increase risk of ischemic injury.
What is the typical maximum cold storage time for skin grafts in a tissue bank?
7 days
14 days
30 days
21 days
Skin grafts stored in proprietary solutions at 4°C are generally viable for up to 21 days. Beyond this period, cell viability and structural integrity decline significantly.
A donor lung was recovered 2 hours after cross-clamp and then underwent 4 hours of cold storage. If the maximum acceptable cold ischemia is 6 hours, how many hours of cold storage remain before transplantation?
4 hours
1 hour
2 hours
0 hours
Cold ischemia begins once the lung is flushed and cooled. With a total limit of 6 hours and 4 hours already elapsed, 2 hours of safe storage remain.
A cornea is recovered 10 hours post-mortem and stored at 4°C. Considering the 12-hour death-to-recovery guideline, is this recovery within acceptable limits?
Yes, within guidelines but viability is reduced
No, but it can be extended to 24 hours
Yes, with no impact on viability
No, it exceeds the limit
Recovery at 10 hours is within the 12-hour post-mortem window for corneal tissue. However, longer post-mortem intervals can lower endothelial cell counts and graft success.
Musculoskeletal tissue must be processed within 48 hours of recovery. If recovery occurs at 14:00 on Monday, by what time must processing be completed?
14:00 on Wednesday
08:00 on Wednesday
08:00 on Thursday
14:00 on Thursday
A 48-hour window from 14:00 Monday expires at 14:00 on Wednesday. Timely processing prevents contamination and maintains tissue quality.
Research indicates that for certain tissues, each 1°C increase above recommended storage temperature reduces viability by 1 hour. If heart tissue is stored at 5°C instead of 4°C, what is the expected reduction in preservation time?
1 hour
0.5 hour
2 hours
4 hours
Elevated storage temperatures accelerate metabolic degradation. A 1°C rise above the ideal cold storage temperature typically cuts viability by about 1 hour for heart tissue.
Under advanced hypothermic machine perfusion protocols, which organ shows the greatest extension of acceptable cold ischemia time?
Pancreas
Liver
Heart
Kidney
Hypothermic machine perfusion has demonstrated significant benefit in kidney transplantation, extending cold ischemia tolerance beyond traditional static storage limits. It reduces delayed graft function rates.
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Learning Outcomes

  1. Identify critical time limits for donor tissue recovery across various organ types.
  2. Analyze regulatory guidelines to ensure compliant retrieval practices.
  3. Apply best practices to optimize graft viability within recovery windows.
  4. Evaluate clinical scenarios to determine allowable extraction deadlines.
  5. Demonstrate understanding of factors impacting tissue preservation and safety.

Cheat Sheet

  1. Master organ recovery windows - Organs have strict post-recovery time limits: hearts and lungs need transplantation within 4 - 6 hours, whereas kidneys can wait 24 - 36 hours before transplant. Familiarizing yourself with these deadlines helps coordinate logistics and ensures graft success. Time really is of the essence! New York State Donate Life Registry
  2. Chill fast, recover longer - Prompt cooling of donor bodies extends procurement windows dramatically. If cooling happens within 6 hours, you can stretch recovery up to 48 hours; otherwise, you must work within a 12-hour limit. Remember: "Cool within six, recover within forty-eight." JPAC Transfusion & Transplantation Guidelines
  3. Corneal clock: 72-hour window - Corneas can be harvested up to 72 hours after death without losing quality, which greatly boosts donor availability. This resilient tissue gives you more breathing room when planning recovery. Keep in mind: "Corneas are resilient up to seventy-two." PubMed
  4. Follow AATB ischemia rules - Regulatory standards from the American Association of Tissue Banks cap ischemic time for cardiac and vascular tissues at 48 hours. Adhering to these guidelines ensures both compliance and tissue safety. Always check the latest bulletins before every retrieval. American Association of Tissue Banks
  5. Minimize warm ischemia - Cutting down on warm ischemic time and using aseptic retrieval methods maximizes graft viability and patient outcomes. "Less warm time, more graft prime" isn't just a catchy phrase - it's best practice. Implementing these habits consistently boosts transplant success rates. PMC Study
  6. Match tissue to time limits - Each tissue type has unique deadlines: corneas are forgiving, while heart valves demand lightning-fast action. Assess scenarios carefully to decide the best recovery timeline for each tissue. Tailor every plan to the organ or tissue at hand. JPAC Transfusion & Transplantation Guidelines
  7. Choose the right preservation method - Cryopreservation keeps cells alive in near-native state, while freeze-drying extends shelf life at the cost of rehydration prep. Picking the perfect technique balances clinical needs and tissue type. Dive into each method's pros and cons for optimal results. Allograft Academy Preservation Methods
  8. Balance preservation time & quality - Although longer cornea preservation can reduce endothelial cell density, research shows success even after 11 days. Weigh the pros and cons to optimize graft health. Sometimes patience pays off - up to a point! NIH Study
  9. Beat contamination with speed - Delay spells disaster: extended recovery times can hike tissue bioburden and infection risk. Swift procurement combined with proper cooling is your best defense. Remember: "Quick recovery keeps contamination at bay." PMC Research
  10. Keep up with evolving standards - Guidelines aren't set in stone - AATB updates time limits as new evidence emerges. Regularly checking their bulletins keeps your protocols current, compliant, and safe. Continuous learning leads to continuous improvement! American Association of Tissue Banks
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