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Quizzes > Quizzes for Business > Healthcare

Take the Monkeypox Knowledge Assessment Quiz

Evaluate your understanding of monkeypox transmission

Difficulty: Moderate
Questions: 20
Learning OutcomesStudy Material
Colorful paper art promoting a Monkeypox Knowledge Assessment Quiz.

Ready to test your grasp of monkeypox facts? This monkeypox quiz is our Knowledge Assessment Quiz, guiding healthcare students and professionals through 15 insightful questions on symptoms, transmission, and prevention. Ideal for boosting virus awareness and clinical readiness, it delivers instant feedback to reinforce learning. You can freely adjust every question in our intuitive editor, similar to the Training Knowledge Assessment Quiz you've seen. Explore more quizzes to expand your skillset.

Which of the following is a characteristic symptom of monkeypox?
Petechial hemorrhages
Maculopapular rash evolving to pustules
Blue”green skin discoloration
Honeycomb skin lesions
Monkeypox typically presents with a maculopapular rash that progresses to pustules over several days. This progression is a hallmark of monkeypox infection and helps distinguish it from other rash”causing illnesses.
What is the primary route of human-to-human transmission of monkeypox virus?
Vector”borne transmission by mosquitoes
Fecal-oral route
Ingestion of contaminated water
Direct contact with lesion material
Direct contact with the fluid from monkeypox skin lesions is the main mode of transmission between humans. Respiratory droplets can also spread the virus but direct lesion contact carries the highest risk.
What is the typical incubation period for monkeypox after exposure?
21 - 28 days
30 - 40 days
1 - 3 days
7 - 14 days
The incubation period for monkeypox generally ranges from 7 to 14 days, though it can vary from 5 to 21 days. Knowing this timeframe helps with contact tracing and monitoring exposed individuals.
Which animal group is considered a reservoir for monkeypox virus in endemic areas?
Birds such as parrots
Rodents such as squirrels and rats
Primates only
Reptiles such as lizards
Various rodents, including certain squirrels and rats, are thought to serve as reservoir hosts for monkeypox in endemic regions. Primates and humans are typically spillover hosts rather than long-term reservoirs.
Which symptom is NOT commonly associated with monkeypox infection?
Jaundice
Lymphadenopathy
Rash with pustules
Fever
Jaundice is not a feature of monkeypox infection and is more indicative of liver pathology. Monkeypox commonly causes fever, lymphadenopathy, and a characteristic pustular rash.
Which of these tests is the gold standard for diagnosing monkeypox?
PCR testing of lesion swabs
Viral culture in cell lines
Enzyme”linked immunosorbent assay (ELISA)
Hemagglutination inhibition assay
PCR testing of skin lesion material provides rapid and specific detection of monkeypox viral DNA. It is considered the gold standard due to its high sensitivity and specificity.
Which clinical feature helps distinguish monkeypox from chickenpox?
Rapid lesion healing within 24 hours
Prominent lymphadenopathy
Distribution of lesions only on trunk
Presence of cough
Prominent swollen lymph nodes (lymphadenopathy) are a key feature of monkeypox and are typically absent or minimal in chickenpox. This helps clinicians differentiate the two illnesses.
What personal protective equipment (PPE) is recommended for healthcare workers when caring for monkeypox patients?
Surgical gown and gloves only
Cloth mask and apron only
N95 respirator, gown, gloves, and eye protection
Surgical mask and shoe covers only
An N95 respirator plus gown, gloves, and eye protection provide protection against both droplet and contact transmission of monkeypox. Surgical masks alone do not filter small aerosolized particles as effectively.
A patient exposed 2 days ago to a confirmed monkeypox case has negative serology today. Why?
Serologic tests are always negative in monkeypox
Cross-reactivity suppressed antibody response
Antibodies may not develop until 2 - 3 weeks post-exposure
Virus inhibits antibody formation completely
Antibodies to monkeypox virus typically take 2 - 3 weeks to reach detectable levels, so early serologic testing can be falsely negative. PCR of lesion material is preferred in early stages.
Which measure helps prevent fomite transmission of monkeypox in a household?
Cleaning surfaces with an approved disinfectant
Dry dusting only
Using fabric softener on bedding
Frequent hydration of linens
Monkeypox virus can persist on surfaces and fabrics, so disinfecting high”touch areas with EPA-approved agents reduces fomite transmission. Dry dusting can aerosolize particles and is not sufficient.
Which vaccine is recommended as post-exposure prophylaxis for high-risk monkeypox contacts?
ACAM2000 live replicating vaccine
JYNNEOS non-replicating vaccine
BCG vaccine
MMR vaccine
JYNNEOS is a non-replicating vaccinia vaccine approved for monkeypox exposure prophylaxis due to its safety profile. ACAM2000 carries higher risks, especially in immunocompromised individuals.
Prior smallpox vaccination provides approximately what level of protection against monkeypox?
100%
10%
50%
85%
Historical data indicate that smallpox vaccination offers about 85% cross-protection against monkeypox. Immunity wanes over time, but vaccinated individuals still have reduced risk.
A patient with suspected monkeypox has a negative PCR result from a crusted lesion. What is the likely reason?
PCR cross-reacts with bacterial DNA
PCR cannot detect monkeypox in humans
Late sampling when viral DNA is reduced in crust
Lesions contain no virus at any stage
Late in the course of monkeypox, lesion crusts may contain lower viral DNA levels, leading to false-negative PCR. Early vesicular or pustular material yields the most reliable samples.
Which scenario poses the lowest risk for monkeypox transmission?
Shaking hands with an infected person
Sharing towels with an infected person
Casual conversation without close contact
Handling contaminated bedding
Casual conversation without direct contact with lesions or shared items carries minimal transmission risk. The virus requires close contact with lesions or contaminated objects to spread effectively.
Why is serology alone not sufficient for definitive monkeypox diagnosis?
Antibody cross-reactivity with other orthopoxviruses
Virus does not elicit antibody responses
Blood tests are not permissible in outbreaks
Serology is too expensive
Serologic assays can cross-react with antibodies from other orthopoxvirus exposures, reducing specificity. PCR testing of lesion material remains the most accurate diagnostic approach.
An HIV-positive patient with CD4 count 80 presents with extensive monkeypox lesions. Which antiviral is recommended?
Acyclovir
Tecovirimat (TPOXX)
Oseltamivir
Zidovudine
Tecovirimat is the first-line antiviral approved for treatment of severe monkeypox cases, including in immunocompromised patients. Other antivirals like acyclovir are ineffective against orthopoxviruses.
Which rash distribution pattern helps differentiate monkeypox from chickenpox?
Random distribution without pattern
Centripetal distribution more on trunk
Linear distribution along nerve dermatomes
Centrifugal distribution - lesions on face and extremities first
Monkeypox lesions commonly start on the face and extremities (a centrifugal pattern), unlike chickenpox which is centripetal with more lesions on the trunk. This helps in clinical differentiation.
A pregnant healthcare worker with high-risk exposure should receive which vaccine?
JYNNEOS non-replicating vaccine
Measles vaccine
Varicella zoster vaccine
ACAM2000 live replicating vaccine
JYNNEOS is a non-replicating vaccinia vaccine considered safer during pregnancy. ACAM2000 is contraindicated due to risk of fetal vaccinia from its replicating virus.
Which public health strategy is most effective for controlling a localized monkeypox outbreak?
Ring vaccination of contacts and case isolation
Antibiotic prophylaxis for all residents
School closures only
Universal mass vaccination of entire country
Ring vaccination targets contacts of confirmed cases and, when combined with isolation, effectively contains spread without mass vaccination. Antibiotics have no role, and school closures alone are insufficient.
A patient develops severe ocular monkeypox lesions risking vision loss. What adjunctive therapy is indicated?
Vaccinia immune globulin (VIG)
Topical acyclovir
Oral amoxicillin
Intravenous immunoglobulin for RSV
Vaccinia immune globulin can be used as adjunctive therapy for severe ocular monkeypox to neutralize virus and reduce inflammation. Antivirals for other viruses do not address poxvirus ocular disease.
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Learning Outcomes

  1. Identify the primary symptoms and transmission routes of monkeypox.
  2. Analyze case scenarios to determine exposure risks.
  3. Evaluate diagnostic methods and assessment accuracy.
  4. Apply prevention strategies in hypothetical situations.
  5. Demonstrate knowledge of treatment protocols and guidelines.
  6. Distinguish monkeypox from similar viral infections.

Cheat Sheet

  1. Symptom Radar - Get to know the telltale signs of monkeypox: fever, headache, muscle aches, swollen lymph nodes, and a rash that evolves from flat spots to raised bumps and finally scabs. Spotting these stages early helps you act fast and get the right care. Keep your eyes peeled for each rash phase - it's your first line of defense in mastering the material. Mayo Clinic - Monkeypox FAQ
  2. Spread Patrol - Monkeypox can hop from person to person through direct contact with infectious sores, scabs, or body fluids. It can even sneak through respiratory droplets when you're face-to-face for a while. Understanding these routes keeps you one step ahead in the transmission game. CDC - Monkeypox Transmission
  3. Contamination Clues - The virus isn't picky - it can also hitch a ride on clothing, bedding, or towels used by someone infected. Always treat shared materials with caution and wash fabrics thoroughly to break the chain of infection. This insight is crucial for real-world prevention. CDC - Handling Contaminated Materials
  4. Exposure Checker - Assess risk by thinking about close physical contact, shared living spaces, or activities like hugging and wrestling. The closer and longer the contact, the higher the chance of spread. Mapping out these scenarios helps you evaluate danger zones in any setting. VUMC - Monkeypox Transmission & Prevention
  5. PCR Detective - Confirmation comes through polymerase chain reaction (PCR) tests on skin lesion samples, giving a definitive yes or no. Learning about PCR's accuracy and timing helps you understand why early testing matters. It's a key skill for anyone studying infectious disease diagnostics. JAMA - PCR Diagnosis of Monkeypox
  6. Prevention Power-Ups - Avoid close contact with infected individuals, practice strict hand hygiene, and don personal protective equipment when needed. Simple habits like washing hands and sanitizing surfaces can make a huge difference. These power-ups form the cornerstone of your infection-fighting toolkit. Mayo Clinic - Prevention Tips
  7. Vaccine Shield - The JYNNEOS vaccine is recommended for those at high risk of exposure, boosting your immune defenses against monkeypox. Understanding who qualifies and how the vaccine works adds depth to your prevention mastery. Think of it as a protective shield in your study arsenal. JAMA - JYNNEOS Vaccination
  8. Treatment Toolkit - While most cases focus on symptom relief - like pain management and wound care - antivirals such as tecovirimat may be used in severe scenarios. Knowing when and why these medications come into play is vital for clinical understanding. Ready your toolkit for both common and critical care strategies. JAMA - Monkeypox Treatment
  9. Differential Detective - Distinguish monkeypox from similar infections like chickenpox or measles by noting unique rash patterns and distribution. Monkeypox lesions often appear simultaneously in one area and progress together - unlike chickenpox's staggered spots. Sharpen this detective skill to avoid diagnostic mix-ups. Wikipedia - Mpox Overview
  10. Info Update HQ - Stay in the loop on current outbreaks, public health guidelines, and research breakthroughs to apply your knowledge in real-time. Subscribing to reliable news feeds and health alerts keeps your study material fresh and relevant. In a fast-changing field, up-to-date info is your secret weapon. Le Monde - Mpox Transmission Insights
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